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Lotoa 7P efuefu (1890208-58-8)

Raw laupepa 7P pulu lea e faʻamalosia ai le neitala o loʻo atiaʻeina neurone amata na maua mai le hippocampus, cerebral cortex, ma le retina. i se meaola faʻataʻitaʻiga o manuʻa optic neula, Raw Compound 7P efuefu sa faʻaalia e faʻaosofia ai le tuputupu aʻe o va-43 mea lelei axons, faʻailoa mai ai o le in vitro neurite tuputupu ae gaioiga o le Raw Compound 7P efuefu faʻaliliu i le faʻamalosia o le faʻafouina o le ola i vivo.

Gaosiga: Faʻaputuga Gaosiga
afī: 1KG / ato, 25KG / talipalau
Wisepowder ei ai le gafatia e gaosia ma tuʻuina atu se aofaʻi tele. Gaosia uma i lalo o le cGMP tulaga ma faiga pulea lelei atoatoa, pepa uma suʻega ma faʻataʻitaʻiga avanoa.
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Lotoa 7P efuefu (1890208-58-8) vitio

 

Lotoa 7P efuefu Base Faʻamatalaga

igoa Lotoa 7P efuefu
CAS 1890208-58-8
Mama Atoatoa i Tulaga 98%
Igoa faʻapitoa 2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide
Synonyms Faʻatasi 7P

CHEMBL3824120

Faiga Faʻavae Molecular C22H23N3O5S
Taumaʻa Masele 441.5 g / mol
Melting Point E tusa o le 159 ℃
InChI Key NAXWKPFXCOBXLE-UHFFFAOYSA-N
faiga malō
Faʻaaliga Lanu pa'epa'e
Afa o le Ola 1-2h
Solubility Soluble i le ethyl acetate, dichloromethan;

Sese solu i metanol; solomuli i

vai

teuina o Meaai a Tuutuuga i se nofoaga matutu, mai le malamalama.
talosaga Lotoa 7p na atiae o se tasi i le faʻasologa o tuʻufaʻatasia ma le faʻamoemoe e faʻailoa le lua-gaioiga thromboxane receptor antagonist / synthase inhibitors.
Pepa o suʻega iai

 

Lotoa 7P efuefu General Description

Raw laupepa 7P pulu lea e faʻamalosia ai le neitala o loʻo atiaʻeina neurone amata na maua mai le hippocampus, cerebral cortex, ma le retina.

I se faʻataʻitaʻiga faʻataʻitaʻi o manuʻa optic saraf, Raw Compound 7P na faʻaalia e faʻaosofia ai le tuputupu aʻe o va-43 mea lelei axons, faʻailoa mai ai o le in vitro neurite tuputupu ae gaioiga o le Raw Compound 7P e faʻaliliu i le faʻatupuina o axon toe faʻafouina i vivo.

 

Lotoa 7P (1890208-58-8) Talafaʻasolopito

Lotoa 7p na atiae o se tasi i le faʻasologa o tuʻufaʻatasia ma le faʻamoemoe e faʻailoa le lua-gaioiga thromboxane receptor antagonist / synthase inhibitors.

Ole mea moni ole 7p o loʻo faʻaalia ai le filifiliina mo prostaglandin I2 synthase (PTGIS, CYP8A1) luga o le thromboxane synthase (CYP5A1).

 

Lotoa 7P (1890208-58-8) Faamanuiaga

  1. Toe lipotia le maamu o le ulu
  2. Faʻalauiloaina le tuputupu aʻe o neurite o loʻo faʻafaileleina neurons na maua mai le hippocampus, cerebral cortex, ma le retina.

 

Lotoa 7P (1890208-58-8) Tele suʻesuʻega

O loʻo tuʻuina atu ni faʻavae talafeagai mo taumafaiga i le lumanaʻi e faʻaleleia atili ai le togafitia.

 

Lotoa 7P (1890208-58-8) Faʻamatalaga

  • Mautinoa, fatufatu mai ma le moli taofi o thiazolidinedione faavae benzene sulphonamide o loʻo i ai pyrazole autu e avea ma malosi aneti-suka suka. Naim MJ, Alam O, Alam MJ, Hassan MQ, Siddiqui N, Naidu VGM, Alam MI. Bioorg Faʻailoga. 2018 Fep; 76: 98-112 doi: 10.1016 / j.bioorg.2017.11.010. Epub 2017 Nov 16. PMID: 29169079
  • Novema 1,3,5-triazine maua ai malosi malosi anti-cervical kanesa aafiaga e ala i le faʻalelei o le Bax, Bcl2 ma Caspases faʻaaliga. Wang X, Yi Y, Lv Q, Zhang J, Wu K, Wu W, Zhang W. Chem Biol Fualaau Fualaau 2018 Mati; 91 (3): 728-734. doi: 10.1111 / cbdd.13133. Epub 2017 Novema 15. PMID: 29068538
  • Gaoioiga mafai ona puipuia le kanesa o le 7-O-pentyl quercetin: Lelei, faʻapitoa-faʻataʻamilomilo kinase inhibition ma le pro-oxidant aafiaga. Sassi N, Mattarei A, Espina V, Liotta L, Zoratti M, Paradisi C, Biasutto L. Pharmacol Res. 2017 Oketopa; 124: 9-19. doi: 10.1016 / j.phrs.2017.07.016. Epub 2017 Iulai 17. PMID: 28728925
  • Indole carboxylic acid esters o melampomagnolide B o malosi malosi ia puipuia ai faʻamalositino e tau i le hematological ma mautu sela sela. Bommagani S, Ponder J, Penthala NR, Janganati V, Jordan CT, Borrelli MJ, Crooks PA. Eur J Med Chem. 2017 Aukuso 18; 136: 393-405. doi: 10.1016 / j.ejmech.2017.05.031. Epub 2017 Me 11. PMID: 28525840 Free PMC Mataupu
  • Best Taiala Nootropic Stack: O Mea Uma E Tatau Ona E Iloa [5 Tausaga Aafiaga]

 

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