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Astragaloside IV

Astragaloside IV o se bioactive saponin muamua tuʻu ese mai aʻa mamala aʻa o le ituaiga Astragalus, lea e faʻaaogaina i vailaʻau Saina masani.1 O fualaʻau-faʻalagolagoina taofiofia adenovirus ituaiga tagata 3 (HAdV-3) i A549 sela (IC50 = 23 µM; LC50 = 865 µM) .2 E taofia ai le toe faia o le HAdV-3 ma faʻaititia ai le HoptV-3-faʻaosoina apoptosis. E i ai eseese puipuiga aafiaga mo le fatu, puipuia, digestive, ma neura sisiva.1,3 Ae maise lava, e faʻaititia ai le myocardial infarct tele i maile pe a faʻatautaia muamua o le coronary ligation ma faʻaititia reperfusion.

Gaosiga: Faʻaputuga Gaosiga
afī: 1KG / ato, 25KG / talipalau
Wisepowder ei ai le gafatia e gaosia ma tuʻuina atu se aofaʻi tele. Gaosia uma i lalo o le cGMP tulaga ma faiga pulea lelei atoatoa, pepa uma suʻega ma faʻataʻitaʻiga avanoa.
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Astragaloside IV Powder Base Faʻamatalaga

igoa Astragaloside IV efuefu
CAS 84687-43-4
Mama Atoatoa i Tulaga 50%, 98%
Igoa faʻapitoa Astragaloside IV
Synonyms Astrasieversianin XIV;

cyclosieversioside F;

ASTRAGALOSIDE;

cyclosiversioside F;

Astragalus Polysaccharides;

Upu sii Astragalus;

Faiga Faʻavae Molecular C41H68O14
Taumaʻa Masele 784.97
Melting Point 295-296 ° C (lit.)
InChI Key QMNWISYXSJWHRY-YLNUDOOFSA-N
faiga malō
Faʻaaliga Paʻepaʻe i le samasama samasama pauta
Afa o le Ola /
Solubility Soluble i le methanol, ethanol, acetone; Inoluble inchloroform, ethyl acetate ma isi vaivaʻi polar organic ua vaivai.
teuina o Meaai a Tuutuuga Teu i -20 ° C
talosaga vasodilator, antihypertensive, tetee
Pepa o suʻega iai

 

Astragaloside IV Paʻu 84687-43-4 Faamatalaga Aoao

Astragaloside IV o se pentacyclic triterpenoid o le cycloastragenol o loʻo iai beta-D-xylopyranosyl ma beta-D-glucopyranosyl residues faʻapipiʻi i tulaga O-3 ma O-6 faʻatulagaina. E vavaeʻese mai le Astragalus membranaceus var mongholicus. E i ai lona matafaioi o le EC 4.2.1.1 (carbonic anhydrase) inhibitor, o le anti-inflammatory agents, o le neuroprotective agents, o le antioxidant, o le pro-angiogenic agents ma le plant metabolite. O le sapiterin triterpenoid ma le pentacyclic triterpenoid. E mafua mai i le cycloastragenol.

 

Astragaloside IV Paʻu 84687-43-4 History

O le Astragaloside IV ose tuʻufaʻatasiga o laʻau fualaʻau Saina, ma o aoga taua e aofia ai le teteʻe i le soifua matua, faʻamalosia o le tino, faʻamalieina lelei ma loloto, tuputupu aʻe o lauulu, faʻalauteleina o le libido, ma le anti-inflammatory.

 

Astragaloside IV Paʻu 84687-43-4 Mfaiga OAfaʻasologa

Astragaloside IV o se cycloartane-type triterpene glycosides, o se tasi o aoga autu o vailaʻau Saina vailaʻau Astragalus membranaceus, o lona anotusi o le autu faʻavae mo le iloiloga o le lelei aoga o Astragalus membranaceus. Astragaloside IV ei ai aafiaga i anti-tumo, aneti-inflammatory, vailaʻau, hypoglycemic, puipuiga o le myocardial, anti-viral myocarditis, puipuia sela o le faiʻai ma anti-hepatitis B siama etc..

 

Astragaloside IV Powder 84687-43-4 Sili atu suʻesuʻega

Aʻafiaga tau vailaʻau:

  1. Aafiaga puipuia: Astragaloside IV, isumu peritoneal macrophages ma Mycobacterium tuberculosis na galulue faʻatasi e faʻataʻitaʻia le phagocytic agavaʻa i Mycobacterium tuberculosis o isumu peritoneal macrophages, ma le anotusi o le γ-interferon (IFN-γ) ma interleukin-1β (IL-1β) i le aganuu auala na maitauina foi.
  2. Aafiaga o le puipuia o totoga, e aofia ai Puipuiga o faiʻai, puipuiga o fatugaʻo, puipuiga o le mama, puipuiga o le myocardial, puipuiga o le ate
  3. Aʻafiaga Hypoglycemic: Aveina o isumu ma ituaiga-2 maʻisuka e fai ma suʻesuʻega mea e suʻesuʻe ai le faʻatulafonoina o le astragaloside IV i le hepatic glucose enzymes i isumu ma lena streptomycin ma maualuga-gaʻo meaʻai faʻatosina mai suka.
  4. Aʻafiaga anti-apoptotic: astragaloside IV mafai mafai ona faʻaititia le apoptosis index o myocardial sela ma CVB3 viral myocarditis.
  5. Aneti-inflammatory ma antiviral aafiaga: astragaloside IV na matua faʻatamaia lava le xylene-induced ear edema i isumu, ma le malosi aneti-afaina aafiaga.
  6. Aʻai le faʻasolo i le soifua matua: o le teteʻe i le matua o aafiaga o astragaloside IV e fesoʻotaʻi ma ana gaioiga i le faʻasaʻolotoina o le radical ma le anti-lipid peroxidation, faʻalauteleina le suiga o polotini, faʻamamaina ole nucleic acid metabolic disorders ma faʻalauiloa le faʻateleina ma le apoptosis o fibroblasts o le paʻu o tagata.
  7. Faʻalauteleina le faʻateleina o sela: talafeagai talafeagai o astragaloside IV mafai ona faʻateleina le vave faʻateleina o chondrocytes ma faʻatumauina le gaioiga o chondrocytes, saunia ai se auala fou mo inisinia sela e maua ai le tele o sela sela ma faʻamalie gaioiga gaioiga i se taimi puʻupuʻu.

 

Astragaloside IV Powder 84687-43-4 Faʻasinoga

  1. Zhang, Wei-Jian., Et al., 2003. Faʻamalosi tino e faʻatamaʻi ai le astragaloside IV e faʻatonutonuina e ala i le taofiofia o le faʻatagaina o le NF-kappaB ma faʻamaoniga o le molemole adhesion. Thrombosis ma haemostasis. 90 (5): 904-14. PMID: 14597987
  2. Li M, et al. Astragaloside IV faʻamalosia le mafaufau le atoatoa faʻatosinaina e le tumau cerebral ischemia ma reperfusion i isumu ala i le anti-inflammatory auala. Neurosci Lett. 2016 Tesema 20.
  3. He CS, ma isi. Astragaloside IV Faʻamalosia le Cisplatin Chemosensitivity i le Laʻititi Laʻitiiti Laʻitiiti Kanesa Sulu Kanesa E ala i le Faʻatamaia o B7-H3. Cell Physiol Biochem. 2016; 40 (5): 1221-1229. Epub 2016 Tesema 14.

 

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