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Olivetol (3,5-hydroxypentylbenzene) efuefu (500-66-3)

Olivetol pauu (500-66-3)

Olivetol o se meaola e tupu mai i totonu o le siʻosiʻomaga. E maua i nisi ituaiga o lichens ma e mafai ona vave vavaeina. 5-Pentylresorcinol e maua mai foʻi i le tele o iniseti, a le o se pheromone, repeleti poʻo le antiseptic. O le laau o le cannabis ua maua mai totonu o le mea taua olivetolic acid (OLA), lea na manatu e faʻaaoga e le laʻau e faʻasolosolo faʻapitoa le oloa psychoactive tetrahydrocannabinol (THC).

Gaosiga: Faʻaputuga Gaosiga
afī: 1KG / ato, 25KG / talipalau
Wisepowder ei ai le gafatia e gaosia ma tuʻuina atu se aofaʻi tele. Gaosia uma i lalo o le cGMP tulaga ma faiga pulea lelei atoatoa, pepa uma suʻega ma faʻataʻitaʻiga avanoa.
Talosagaina se Upusii
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Olivetol pauu (500-66-3) vitio

 

 

Olivetol pauu (500-66-3) Faʻamatalaga Faʻavae

igoa Olivetol (3,5-hydroxypentylbenzene) paʻu
CAS 500-66-3
Mama Atoatoa i Tulaga 98%
Igoa faʻapitoa Olivetol
Synonyms 3,5-Dihydroxyamilbenzene; 5-n-Amylresorcinol; 5-n-Pentylresorcinol; 1,3-Dihydroxy-5-pentylbenzene; 5-Pentyl-1,3-benzenediol;
Faiga Faʻavae Molecular C11H16O2
Taumaʻa Masele 180.2435
Melting Point 46-48 ° C (tuʻu.)
InChI Key IRMPFYJSHJGOPE-UHFFFAOYSA-N
faiga malō
Faʻaaliga moli lanumoana e enaena brownstalline
Afa o le Ola /
Solubility Soluble i le vai (vaega miscible), chloroform, ma metanol.
teuina o Meaai a Tuutuuga I totonu o se tau mago ma faʻaavanoa fale teu oloa; aloese mai le la susulu; aloese mai le afi; aloese mai le susu.
talosaga Olivetol e biosynthesized i se polyketide synthase-ituaiga tali mai le hexanoyl-CoA ma tolu moli o malonyl-CoA e se aldol totoʻa o se tetraketide vailauga.
Pepa o suʻega iai

 

Olivetol paula (500-66-3) Aoao Faʻamatalaga

Olivetol sa faʻaaogaina o se ata faʻataʻitaʻi i mea na tutupu i le tuʻufaʻatasiga o le moliga faʻapipiʻi polimeti (MIP). Sa faʻaaogaina foi o se inhibitor o (S) -mephenytoin 4'-hydroxylase gaioiga o faʻafouina CYP2C19.

Olivetol o loʻo faʻaogaina i auala eseese e maua ai le suʻesuʻega faʻataʻitaʻiga o THC.Faʻupuina manaʻomia] O se tasi o na metotia o se tuʻufaʻatasiga o le olivetol ma pulegone. I PiHKAL, Alexander Shulgin lipotia se auala cruder o le gaosia o le oloa lava e tasi i le aumaia i le tali atu olivetol ma le taua suauu o moli i luma o le phosphoryl chloride.

O se metotia mo le tuufaatasia o THC lava ia e aofia ai i luga o le faʻatulagaina o tali i le va o olivetol ma Δ2-carene oxide

 

Olivetol pauu (500-66-3) Talafaʻasolopito

Olivetol e biosynthesized e le polyketide synthase-ituaiga tali mai hexanoyl-CoA ma tolu molemole o malonyl-CoA e ala i le aldol condencies o se tetraketide vavalalata. I le 2009, Taura et al. na mafai ona faʻataʻamilo se ituaiga III PKS faʻaigoa o le olivetol synthase (OLS) mai Cannabis sativa. Lenei PKS o se homodimeric porotini e aofia ai le 385 amino acid polypeptide ma le lapoʻoa vaega o 42,585 Da o loʻo maualuga faʻasologa tutusa (60-70%) faʻailoga e toto ai PKS's.

 

Olivetol paula (500-66-3) Talosaga

1, Faʻaaogaina e fai ma fale gaosi oloa tau vailaʻau.

2, Faʻaaogaina e pei ole Organic Intermediate.

3, Faʻaaogaina e avea ma faʻamautu o lipopolysaccharides, carrageenan ma sialic acid.

 

Olivetol paula (500-66-3) Tele suʻesuʻega

O le gaosiga, umiaina, ma / poʻo le faʻasoasoaina o olivetol e le faʻatagaina e se atunuʻu; peitai, i totonu o le Iunaite Setete, o se DEA na vaaia.

 

Olivetol paula (500-66-3) Tusitusiga

  • Kumano, T., et al .: Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., et al .: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al.: Food Chem., 115, 1170 (2009),
  • . Jiang R, et al. Cannabidiol o se malosi malosi o le gaioiga gaioiga o le cytochrome P450 2C19. Vailaau Metab Pharmacokinet. 2013; 28 (4): 332-8.
  • . Yamaori S, et al. Cannabidiol, o le tele o phytocannabinoid, o se malosi malosi atypical inhibitor mo CYP2D6. Fualaau Metab Dispos. 2011 Nov; 39 (11): 2049-56.

 

Tusitusiga masani

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