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Faʻatau HBT1 efuefu (489408-02-8) hplc≥98% - Gaosi oloa & fale gaosi

HBT1 efuefu (489408-02-8)

O le HBT1 pauu o le AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] malosi e faʻatupuina ai le gaosia o le faiʻai o le neurotrophic factor (BDNF) ma faʻaalia se laititi o tiga tiga i neurons tulaga. HBT1 e fusifusia i le ligand-fusia vaega ole AMPA-R i le glutamate faʻalagolago i auala.

Gaosiga: Faʻaputuga Gaosiga
afī: 1KG / ato, 25KG / talipalau
Wisepowder ei ai le gafatia e gaosia ma tuʻuina atu se aofaʻi tele. Gaosia uma i lalo o le cGMP tulaga ma faiga pulea lelei atoatoa, pepa uma suʻega ma faʻataʻitaʻiga avanoa.
Talosagaina se Upusii
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HBT1 efuefu (489408-02-8) vitio

 

HBT1 efuefu (489408-02-8) Faʻamatalaga Faʻavae

igoa HBT1 efuefu
CAS 489408-02-8
Mama Atoatoa i Tulaga 98%
Igoa faʻapitoa 2-(((5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
Synonyms HBT1; HBT-1; HBT 1
Faiga Faʻavae Molecular C16H17F3N4O2S
Taumaʻa Masele 386.39
Melting Point /
InChI Key PHLXSNIEQIKENK-UHFFFAOYSA-N
faiga paʻu
Faʻaaliga paʻepaʻe papaʻe
Afa o le Ola /
Solubility DMSO: 2 mg / mL, manino
teuina o Meaai a Tuutuuga 0 - 4 C mo se taimi puʻupuʻu (aso i vaiaso), poʻo le -20 C mo se taimi umi (masina).
talosaga Potentiator talimalo AMPA
Pepa o suʻega iai

 

HBT1 efuefu (489408-02-8) Aoao Faamatalaga

HBT1 efuefu o le AMPA receptor potentiator ma maualalo agonistic aafiaga, aloese mai logo-foliga tali i vitro BDNF gaosiga. O le AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator e faʻatupuina le gaosiaina o le faiʻai na maua mai le faiʻai (BDNF) ma faʻaali ai sina aʻafiaga tiga i le tulaga muamua neu HBT1 fusifusia i ligand-fusifusia vaega o AMPA-R i glutamate faʻalagolago faiga.

 

HBT1 efuefu (489408-02-8) Faʻaaliga

[1] Kunugi A, Tajima Y, Kuno H, Sogabe S, Kimura H. HBT1, o le Novel AMPA Receptor Potentiator ma le Lower Agonistic Effect, Aloese mai le Bell-Shaped Response i le Vitro BDNF Production. J Pharmacol Exp Ther. 2018 Mati; 364 (3): 377-389. faia: 10.1124 / jpet.117.245050. Epub 2018 Ian 3. PubMed PMID: 29298820.
 

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