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Emoxypine pauu (2364-75-2)

Emoxipine pauu e faʻaaogaina mo le togafitia o subconjunctival hemorrhages ma intraocular hemorrhages, angioretinopathy, totonugalemu ma peripheral chorioretinal dystrophy, thrombosis o le totonugalemu o le totino ma ona lala, ma isi.

Gaosiga: Faʻaputuga Gaosiga
afī: 1KG / ato, 25KG / talipalau
Wisepowder ei ai le gafatia e gaosia ma tuʻuina atu se aofaʻi tele. Gaosia uma i lalo o le cGMP tulaga ma faiga pulea lelei atoatoa, pepa uma suʻega ma faʻataʻitaʻiga avanoa.
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Emoxypine pauu (2364-75-2) vitio

 

Emoxypine pauu Base Faʻamatalaga

igoa Emoxypine pauu
CAS 2364-75-2
Mama Atoatoa i Tulaga 98%
Igoa faʻapitoa Mexidol; Mekisifi
Synonyms Emoxipine, Emoxypin, Epigid, 6-Methyl-2-ethyl-3-hydroxypyridine
Faiga Faʻavae Molecular C8H11NO
Taumaʻa Masele 137.179 g g / mol
Melting Point 170 i le 172 ° C
InChI Key JPGDYIGSCHWQCC-UHFFFAOYSA-N
faiga malō
Faʻaaliga Paʻepaʻe e Paʻepaʻe paʻu paʻu
Afa o le Ola 2-2.6 itula
Solubility Matua suamalie i le vai; DMSO (Laulau); Metanol (Lemu)
teuina o Meaai a Tuutuuga 0 - 4 C mo se taimi puʻupuʻu (aso i vaiaso), poʻo le -20 C mo se taimi umi (masina).
talosaga RAD140 o se suʻesuʻe ma e le o ni vailaʻau faʻasolosolo androgen receptor modulator (SARM) mo le togafitia o tulaga e pei o maso maso ma kanesa o le susu.
Pepa o suʻega iai

 

Emoxypine pauu Aoao Faamatalaga

Emoxypine (2-ethyl-6-methyl-3-hydroxypyridine) paʻu, e taʻua foi o Mexidol po o Mexifin pe a faʻaaogaina o le succinate masima, o se antioxidant gaosia i Rusiaby Pharmasoft Pharmaceuticals. O lona fausaga vailaʻau foliga tutusa ma le pyridoxine (o se ituaiga o vitamini B6).

 

Emoxypine pauu (2364-75-2) Talafaʻasolopito

O le Emoxypine paʻu na muamua faʻatulaga e LD Smirnov ma KM Dumayev, ona suʻesuʻeina lea ma atinaʻe i le Institute of Pharmacology, Russian Academy of Medical Sciences ma le National Scientific Center of Bioactive Substances Safety.

 

Emoxypine (2364-75-2) Faʻavae o Gaioiga

O le faʻataʻitaʻiga a Emoxypine o le gaioiga e talitonuina o ona antioxidant ma membrane-puipuia aafiaga ma vaega taua nei:

  • Emoxypine taofia le faasaolotoina faʻaosofia o le biomembrane lipids, tali atu i le peroxide rads o lipids primer ma hydroxyl radial o peptides
  • Faateleina le gaioiga o antioxidant enzymes, aemaise o le superoxide dismutase, nafa ma le fausiaina ma le taumafaina o lipid peroxides ma malosi okesene foliga
  • Taofiofia saoloto rads i le taimi o le tuufaatasiga o prostaglandin catalyzed cyclooxygenase ma lipoxygenase, faʻateleina le faʻatulagaina prostacyclin / thromboxane A2ma poloka le leukotriene fausia
  • Faateleina le anotusi o polar fraction o lipids (phosphatidyl serine ma phosphatidyl inositol) ma faʻaititia le kolose / phospholipids fua faatatau e faʻamaonia ai le lipid-tulafono faatonutonu; suiga suiga i suiga o le vevela sone, o le faʻaoso lea o le faʻaititia o membrane viscosity ma le faʻaopopoina o lona suavai, faʻateleina lipid-protein ratio.
  • Faʻatonutonuina le gaioiga o fusi-fusifusi enzymes: phosphodiesterase, cyclicnucleotides, adenylate cyclase, aldoreductase, acetylcholinesterase.
  • Faʻataʻitaʻia ia mea e fai e siama o le faiʻai, pei o le benzodiazepine, GABA, acetylcholine receptors e ala i le faʻalauteleina o latou malosi faʻatulagaina.
  • Faʻamalosia biomembranes, ie membrane fausaga o sela toto - erythrocytes ma thrombosit i le taimi o latou haemolysis poʻo manuʻa manuʻa faʻatasi ma le faʻavaeina o saoloto radicals.
  • Suia le monoamine tulaga ma faʻateleina le dopamine mea i totonu o le faiʻai.

Emoxypine (2364-75-2) Talosaga

I Lusia, ole emoxypine e tele lona lautele i faʻafomaʻi. E faʻatatauina le faʻamalositino, anti-stress, anti-alkohol, anticonvulsant, nootropic, neuroprotective ma gaioiga tetee. O le Emoxypine e ono faʻaleleia le toto i le cerebral, e taofia ai le faʻaputuputuina o le thrombocyte, faʻaititia ai le maualuga o le kolisi, e iai le gaioiga faʻa-cardioprotective ma le antiatherosclerotic.

 

Emoxypine (2364-75-2) Tele Suʻesuʻega

Tasi lea suʻesuʻega na fuafuaina le aoga o le emoxypine i le 205 tagata gasegase e iai faʻamaoniga o le lumbosacral radiculopathy (LSR). O tagata gasegase na vaevaeina i vaega e lua, ma na vaeluaina foʻi i vaega laiti e faʻalagolago i le i ai o faʻalavelave o le afi. O tagata gasegase uma na mauaina se vasega masani o togafitiga faʻafomaʻi ma faʻaletino; vaega autu maua faaopoopo emoxypine. Ina ua maeʻa, na faia faʻataʻitaʻi-neʻi faʻatonutonu le ova taimi o faʻaiuga o togafitiga i vaega o tagata mamaʻi. O iʻuga na faʻaalia ai o le faʻaaogaina o le emoxypine i le tuʻufaʻatasiga o tagata ma LSR na mafua ai le faʻaititia ma le faʻaauau o le ogaoga o le tiga tiga ma le vave toe faʻaleleia o le gaioiga o aʻa ma neura peripheral faʻatusatusa i togafitiga masani.

 

Emoxypine (2364-75-2) Faʻamatalaga

[1] Dumayev KM, Voronina TA, Smirnov LD antioxidants i le profilaks ma togafitiga o CNS. Moscow, 1995

[2] Kucheryanu, VG (Ianuari 2001). "Mexidol faʻamalosia antiparkinsonian aafiaga o L-DOPA i MPTP-faʻaosofia parkinsonism faʻataʻitaʻi". Eksperimental'naia i klinicheskaia farmakologiia. 64 (1): 22-25.

[3] Likhacheva, EB; Sholomov, II (2006). "Suʻesuʻega ole falemaʻi male tui puipuia ole aoga ole mexidol ile togafitiga ole lumbosacral radiculopathy". ZhurnalNevrologii i Psikhiatrii Imeni SS Korsakova. 106 (10): 52–7.
 

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